Psilocybin, Depression and Cancer

COMPASS Pathways, a mental health care company dedicated to accelerating patient access to evidence-based innovation in mental health, welcomed the topline data shared today from an open-label study of psilocybin therapy for depression in cancer patients.

Within one week of a single administration of COMP360 psilocybin therapy, 50% of participants achieved remission in depression symptoms, which was sustained for the eight week follow-up period.

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Latest Research on Psychedelics and Depression

Here’s the latest on how there is a shift in psychiatry toward a new way of thinking about depression, its causes, and therapies.

The profession’s long embrace of the “monoamine hypothesis” — the idea that depression primarily results from abnormal levels of neurotransmitter chemicals in the brain and that drugs can restore the proper balance — is giving way to a more complex understanding and alternative treatments, from ketamine to psychedelics to magnetic stimulation.

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Ayahuasca and Depression

The antidepressant effects of the psychedelic brew known as ayahuasca appear to be related to anti-inflammatory activity, according to new research from scientists in Brazil.

Their findings, published in the Journal of Psychopharmacology, provide new insights into the biological mechanisms behind the observed antidepressant effects of the substance.

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