Psychedelics and Prolonged Grief Disorder

Psychedelics such as psilocybin and MDMA may be a promising treatment avenue for Prolonged Grief Disorder (PGD).

Randomized clinical trials demonstrated the efficacy of psilocybin in reducing symptom severity in depression and MDMA in reducing PTSD symptomatology.

Furthermore, psychedelics often produce subjective effects (such as transcendence, mystical experiences, and a sense of oneness) that may be uniquely relevant to the existential distress experienced in PGD.

Read more

Psychological Flexibility and Psychedelics

In a new study, researchers found that psychological flexibility, several facets of mindfulness, and values-congruent living significantly improved following psilocybin and were maintained through week 16.

Additionally, improvements in psychological flexibility and experiential acceptance were strongly associated with reductions in depression severity following psilocybin.

Keep reading for the full article at Nature.com

Read more