Psychedelics and Mental Health: Recent Research

Psychedelic drugs can induce mind-altering states affecting perception, thought and sensory input.

They have historically been known for their recreational use and do not have nationwide legal approval.

However, psychedelic drugs are also increasingly being studied for their medical benefits (particularly with regard to mental health).

Learn more below about how certain psychedelics can—and cannot—be used for mental wellness.

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Video: Psychedelics, Consciousness, and Creativity

Could psychedelics make you more creative? Shift your mind, connect you to others, and help you access a younger, more malleable version of yourself? Activist Rick Doblin, neuroscientist Gül Dölen, and musician Reggie Watts join Brian Greene for a mind-bending and multidisciplinary conversation about the promises and pitfalls of these "magic" molecules and their impact on creativity, connection, and consciousness.

This program is part of the Big Ideas series, supported by the John Templeton Foundation.

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How Psilocybin May Rewire the Brain

“One of the most interesting things we’ve learned about the classic psychedelics is that they have a dramatic effect on the way brain systems synchronize, or move and groove together,” said Matthew Johnson, a professor in psychedelics and consciousness at Johns Hopkins Medicine.

“When someone’s on psilocybin, we see an overall increase in connectivity between areas of the brain that don’t normally communicate well,” Johnson said. “You also see the opposite of that – local networks in the brain that normally interact with each other quite a bit suddenly communicate less.”

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