Studying Psychedelics- Design and Research

How much does a person’s subjective experience and expectation of a psychedelic trip, as opposed to only the drug’s chemical effects on the brain, influence the drug’s ability to alleviate conditions like depression, addiction, or post-traumatic stress disorder?

Now that psychedelics are being noticed by federal regulators and the public, scientists are again asking: What’s the best way to study these compounds in order to truly understand their effects?