Indigenous Cultures and the Psychedelic Movement

The connection between the psychedelic movement and Indigenous medicine is complex and multifaceted.

Indigenous-led Medicine conservation is biocultural conservation.

It is NOT an effort to simply preserve these medicines (and supply chains) – or their constituent molecules and/or specific habitat – but the entire ecological, social and cultural milieus within which they exist, and from which they cannot be separated without compromising the system as a whole.

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Can Microdosing Hurt the Heart?

Psychedelics like psilocybin, MDMA, LSD, and DMT act on serotonin receptors, and previous research has found that other drugs that act on serotonin receptors can cause fibrosis, or the thickening of heart valves.

That, in turn, can lead to serious or even fatal heart issues like arrhythmias or valvular heart disease.

So far, there’s been little research on the link between repeated psychedelics use and heart health, but this week, researchers at the University of Fribourg Center for Psychiatric Research in Switzerland published a paper in the Journal of Psychopharmacology reviewing the existing evidence.

“It is possible that chronic microdosing may carry a risk of fibrosis and valvular heart disease, which should be assessed in future studies,” the authors write.

“Any future work considering longer microdosing regimens should incorporate breaks and regular screening for vascular abnormalities.”