In 2020, Oregon was the first state in the U.S. to effectively legalize psilocybin, the hallucinogenic component of magic mushrooms, for therapeutic use.
It has shown to be effective in treating post-traumatic stress disorder, depression and end-of-life anxiety.
Since then, regulations and restrictions for psilocybin treatment have taken shape across the state with many rural counties opting out of providing any psilocybin-related services at all.
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Inside the scientific debate that’s shaping the future of psychedelic therapy: To trip or not to trip?
Can the magic be removed from the mushroom — and should it?
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The Global Drug Survey 2020 is a large online survey on drug use collected between November 2019 and February 2020.
Positive changes were observed across all 17 outcome items, with the strongest benefits on items related to insight and mood. Negative effects were reported by 22.5% of respondents.
High intensity of psychedelic experience, seeking advice before treatment, treating with psilocybin mushrooms and treating post-traumatic stress disorder were associated with higher scores on the self-treatment outcome scale after averaging values across all 17 items.
Younger age, high intensity of experience and treating with LSD were associated with increased number of negative outcomes.
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Compass Pathways published the long awaited results of its phase 2 clinical trial for the treatment of depression with psilocybin–assisted psychotherapy in the New England Journal of Medicine.
Psilocybin showed rapid antidepressant effects for most patients, but only 1 in 5 participants showed significant improvement at 12 weeks.
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Is it all hype or is there genuine hope for therapeutic application of microdosing?
There’s certainly plenty of ‘conflicting’ information or results available from studies of different methodologies. Here, we begin with an overview of what microdosing is, who does it, and for what purposes. We then review available evidence and summarize benefits and risks of microdosing. Finally, we get more practical and discuss microdosing regimens, measurement of accurate dosing, and ‘set and setting’ consideration to microdosing.
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New research reveals that the psychedelic compound in magic mushrooms, in combination with talk therapy, could be a promising treatment for people with alcohol addiction.
In a study published Wednesday in JAMA Psychiatry, scientists found that patients taking this drug, called psilocybin, had an 83 percent decline in heavy drinking, while those who took a placebo experienced a 51 percent decline.
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